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Expression and functional studies of the GDNF family receptor alpha 3 in the pancreas.
Nivlet L(1), Herrmann J(1), Martin DE(1), Meunier A(1), Orvain C(1), Gradwohl G(2).
J Mol Endocrinol Feb 2016
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STAT3 modulates beta-cell cycling in injured mouse pancreas and protects against DNA damage.
De Groef S(1), Renmans D(1), Cai Y(1), Leuckx G(1), Roels S(1), Staels W(1,)(2,)(3), Gradwohl G(4), Baeyens L(1,)(5), Heremans Y(1), Martens GA(1,)(6), De Leu N(1,)(7,)(8), Sojoodi M(1), Van de Casteele M(1), Heimberg H(1).
Cell Death Dis 23 juin 2016
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Differentially Expressed MicroRNA-483 Confers Distinct Functions in Pancreatic beta- and alpha-Cells.
Mohan R(1), Mao Y(1), Zhang S(1), Zhang YW(2), Xu CR(2), Gradwohl G(3), Tang X(4).
J Biol Chem 7 août 2015
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Pairing-up SOX to kick-start beta cell genesis.
Grapin-Botton A(1), Seymour PA, Gradwohl G.
Diabetologia May 2015
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Pak3 promotes cell cycle exit and differentiation of beta-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice.
Piccand J, Meunier A, Merle C, Jia Z, Barnier JV, Gradwohl G.
Diabetes Jan 2014
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Rfx6 maintains the functional identity of adult pancreatic beta cells.
Piccand J(1), Strasser P(1), Hodson DJ(2), Meunier A(1), Ye T(1), Keime C(1), Birling MC(3), Rutter GA(2), Gradwohl G(4).
Cell Rep 24 décembre 2014
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Short-term overexpression of VEGF-A in mouse beta cells indirectly stimulates their proliferation and protects against diabetes.
De Leu N, Heremans Y, Coppens V, Van Gassen N, Cai Y, D'Hoker J, Magenheim J, Salpeter S, Swisa A, Khalaileh A, Arnold C, Gradwohl G, Van de Casteele M, Keshet E, Dor Y, Heimberg H.
Diabetologia Jan 2014
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Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice.
Baeyens L(1), Lemper M(2), Leuckx G(2), De Groef S(2), Bonfanti P(2), Stangé G(2), Shemer R(3), Nord C(4), Scheel DW(5), Pan FC(6), Ahlgren U(4), Gu G(6), Stoffers DA(7), Dor Y(3), Ferrer J(8), Gradwohl G(9), Wright CV(6), Van de Casteele M(2), German MS(5), Bouwens L(2), Heimberg H(2).
Nat Biotechnol Jan 2014
