IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Researchers

  Hinrich GRONEMEYER

• Post-Doctoral Fellowships

  Megan ASTLE

  Marco Antonio MENDOZA PARRA

  Shankara Narayanan PATTABHIRAMAN

  Valeria PAVET-PORTAL

  Maximiliano PORTAL

• Phd Students

  Cathrin SCHULZ

  Jelena VJETROVIC

• Engineers & Technicians

  Cathie ERB

  Michèle LIEB

  Malgorzata NOWICKA

  Judith VALLET

  Wouter VAN GOOL

• Administration

  Irène YUJNOVSKY

Functional genomics & cancer

From nuclear receptor action to novel paradigms for cancer therapy action

Publications

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• Design and Stereoselective Synthesis of Retinoids with Ferrocene or N-Butylcarbazole Pharmacophores that Induce Post-Differentiation Apoptosis in Acute Promyelocytic Leukemia Cells

  Ivanova D., Gronemeyer H., de Lera A.R.

  ChemMedChem Aug. 1, 2011 ; 6:1518-29 .

• Epigenetic profiling of the antitumor natural product psammaplin A and its analogues

  Garcia J., Franci G., Pereira R., Benedetti R., Nebbioso A., Rodriguez-Barrios F., Gronemeyer H., Altucci L., Lera A.R.

  Bioorg Med Chem June 15, 2011 ; 19:3637-49 .

• Methylation specifies distinct estrogen-induced binding site repertoires of CBP to chromatin

  Ceschin D.G., Walia M., Wenk S.S., Duboe C., Gaudon C., Xiao Y., Fauquier L., Sankar M., Vandel L., Gronemeyer H.

  Genes Dev June 1, 2011 ; 25:1132-46 .

• Regulator of Calcineurin 1 (RCAN1) Facilitates Neuronal Apoptosis through Caspase-3 Activation

  Sun X., Wu Y., Chen B., Zhang Z., Zhou W., Tong Y., Yuan J., Xia K., Gronemeyer H., Flavell R.A., Song W.

  J Biol Chem March 18, 2011 ; 286:9049-62 .

• Retinoic acid receptor modulators: a perspective on recent advances and promises

  Alvarez S., Bourguet W., Gronemeyer H., de Lera A.R.

  Expert Opin Ther Pat Jan 2011 ; 21:55-63 .

• Single-tube linear DNA amplification (LinDA) for robust ChIP-seq

  Shankaranarayanan P., Mendoza-Parra M.A., Walia M., Wang L., Li N., Trindade L.M., Gronemeyer H.

  Nat Methods 2011 ; 8:565-7 .

• Targeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis

  Kedinger V., Muller S., Gronemeyer H.

  Mol Cancer 2011 ; 10:34 .

• The 12th international conference on differentiation therapy: targeting the aberrant growth, differentiation and cell death programs of cancer cells

  Pettersson F., Miller W.H., Nervi C., Gronemeyer H.J., Licht J., Tallman M.S., Waxman S.

  Cell Death Differ Jul 2011 ; 18:1231-3 .