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750 employés
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Publications de Yann HERAULT

  • A new mouse model of ARX dup24 recapitulates the patients' behavioural and fine motor alterations.

    Dubos A(1)(2)(3)(4), Meziane H(4), Iacono G(5), Curie A(6), Riet F(4), Martin C(7), Loaec N(8), Birling MC(4), Selloum M(4), Normand E(7)(9), Pavlovic G(4), Sorg T(4), Stunnenberg HG(5), Chelly J(1)(2)(3)(10), Humeau Y(7), Friocourt G(8), Herault Y(1)(2)(3)(4).

    Hum Mol Genet 5 avril 2018

  • Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

    Rozman J(1)(2), Rathkolb B(1)(2)(3), Oestereicher MA(1), Schutt C(1), Ravindranath AC(2)(4), Leuchtenberger S(1), Sharma S(2)(5), Kistler M(1), Willershauser M(6)(7)(8), Brommage R(1), Meehan TF(9), Mason J(9), Haselimashhadi H(9); IMPC Consortium, Hough T(10), Mallon AM(10), Wells S(10), Santos L(10), Lelliott CJ(11), White JK(11)(12), Sorg T(13)(14)(15)(16)(17), Champy MF(13)(14)(15)(16)(17), Bower LR(18), Reynolds CL(19), Flenniken AM(20)(21)(22), Murray SA(12), Nutter LMJ(20)(21), Svenson KL(12), West D(23), Tocchini-Valentini GP(24), Beaudet AL(20)(21), Bosch F(25), Braun RB(12), Dobbie MS(26), Gao X(27), Herault Y(13)(14)(15)(16)(17), Moshiri A(28), Moore BA(29), Kent Lloyd KC(18), McKerlie C(20)(21), Masuya H(30), Tanaka N(30), Flicek P(9), Parkinson HE(9), Sedlacek R(31), Seong JK(32), Wang CL(33), Moore M(34), Brown SD(10), Tschop MH(2)(35)(36), Wurst W(37)(38)(39)(40), Klingenspor M(6)(7)(8), Wolf E(2)(3), Beckers J(1)(2)(41), Machicao F(42), Peter A(2)(42)(43), Staiger H(2)(43)(44), Haring HU(2)(42)(43), Grallert H(2)(5)(45), Campillos M(2)(4), Maier H(1), Fuchs H(1), Gailus-Durner V(1), Werner T(46), Hrabe de Angelis M(47)(48)(49).

    Nat Commun 18 janvier 2018

  • Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome.

    Iacono G(1), Dubos A(2)(3)(4)(5), Meziane H(2), Benevento M(6)(7)(8), Habibi E(1), Mandoli A(1), Riet F(2), Selloum M(2), Feil R(9)(10), Zhou H(1)(7), Kleefstra T(7)(8), Kasri NN(6)(7)(8), van Bokhoven H(6)(7)(8), Herault Y(2)(3)(4)(5), Stunnenberg HG(1).

    Nucleic Acids Res 15 mars 2018

  • Nox4 genetic inhibition in experimental hypertension and metabolic syndrome.

    Bouabout G(1), Ayme-Dietrich E(2), Jacob H(1), Champy MF(1), Birling MC(1), Pavlovic G(1), Madeira L(2), Fertak LE(1), Petit-Demouliere B(1), Sorg T(1), Herault Y(1), Mudgett J(3), Monassier L(4).

    Arch Cardiovasc Dis Jan 2018

  • A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse.

    Daubeuf F(1)(2), Becker J(3), Aguilar-Pimentel JA(4), Ebel C(5), Hrabe de Angelis M(4), Herault Y(3)(5)(6)(7)(8), Frossard N(1)(2).

    Curr Protoc Mouse Biol 19 juin 2017

  • A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

    Bowl MR(1), Simon MM(1), Ingham NJ(2)(3), Greenaway S(1), Santos L(1), Cater H(1), Taylor S(1), Mason J(4), Kurbatova N(4), Pearson S(3), Bower LR(5), Clary DA(5), Meziane H(6), Reilly P(6), Minowa O(7), Kelsey L(8)(9)(10); International Mouse Phenotyping Consortium, Tocchini-Valentini GP(11), Gao X(12), Bradley A(3), Skarnes WC(3), Moore M(13), Beaudet AL(14), Justice MJ(8)(9)(10)(14), Seavitt J(14), Dickinson ME(15), Wurst W(16), de Angelis MH(17), Herault Y(6)(18)(19)(20), Wakana S(7), Nutter LMJ(8)(9)(10), Flenniken AM(8)(9)(10), McKerlie C(8)(9)(10), Murray SA(21), Svenson KL(21), Braun RE(21), West DB(22), Lloyd KCK(5), Adams DJ(3), White J(3), Karp N(3), Flicek P(4), Smedley D(23), Meehan TF(4), Parkinson HE(4), Teboul LM(1), Wells S(1), Steel KP(2)(3), Mallon AM(1), Brown SDM(24).

    Nat Commun 12 octobre 2017

  • Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies.

    Wendling O(1), Champy MF(1), Jaubert S(2), Pavlovic G(1), Dubos A(1)(3)(4)(5)(6), Lindner L(1), Jacobs H(1), Mark M(1)(3)(4)(5)(6), Combe R(1), Da Cruz IG(1), Luche H(6), Mudgett JS(7), Rosahl T(7), Sorg T(1), Malissen M(2), Reilly PT(1), Herault Y(8)(9)(10)(11)(12).

    Sci Rep 29 août 2017

  • Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

    Meehan TF(1), Conte N(1), West DB(2), Jacobsen JO(3), Mason J(1), Warren J(1), Chen CK(1), Tudose I(1), Relac M(1), Matthews P(1), Karp N(4), Santos L(5), Fiegel T(5), Ring N(5), Westerberg H(5), Greenaway S(5), Sneddon D(5), Morgan H(5), Codner GF(5), Stewart ME(5), Brown J(5), Horner N(5); International Mouse Phenotyping Consortium, Haendel M(6), Washington N(7), Mungall CJ(7), Reynolds CL(8), Gallegos J(8), Gailus-Durner V(9), Sorg T(10)(11)(12)(13), Pavlovic G(10)(11)(12)(13), Bower LR(14), Moore M(15), Morse I(16), Gao X(17), Tocchini-Valentini GP(18), Obata Y(19), Cho SY(20)(21), Seong JK(20)(22), Seavitt J(8), Beaudet AL(8), Dickinson ME(8), Herault Y(10)(11)(12)(13), Wurst W(9), de Angelis MH(9), Lloyd KCK(14), Flenniken AM(23), Nutter LMJ(23), Newbigging S(23), McKerlie C(23), Justice MJ(24), Murray SA(25), Svenson KL(25), Braun RE(25), White JK(4), Bradley A(4), Flicek P(1), Wells S(5), Skarnes WC(4), Adams DJ(4), Parkinson H(1), Mallon AM(5), Brown SDM(5), Smedley D(3).

    Nat Genet Aug 2017

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